Aging & Longevity

Key Indications

Spermidine and autophagy levels decrease with age in the human organism. Spermidine supplementation may replenish the spermidine pool, induce autophagy in the cells, and prolong life in mice. A long-term epidemiological study demonstrated that higher consumption of spermidine-rich foods correlated with reduced mortality and a 5-year increase in life expectancy.

Human Studies

  • The importance of dietary polyamines in cell regeneration and growth.

  • Higher spermidine intake is linked to lower mortality: a prospective population-based study. Learn More.

Animal Studies

  • Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? Learn More.

  • Induction of autophagy by spermidine promotes longevity.