Spermidine and autophagy levels decrease with age in the human organism. Spermidine supplementation may replenish the spermidine pool, induce autophagy in the cells, and prolong life in mice. A long-term epidemiological study demonstrated that higher consumption of spermidine-rich foods correlated with reduced mortality and a 5-year increase in life expectancy.
The importance of dietary polyamines in cell regeneration and growth.
Higher spermidine intake is linked to lower mortality: a prospective population-based study. Learn More.
Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? Learn More.
Induction of autophagy by spermidine promotes longevity.